World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos One : Analysis of Candidate Colitis Genes in the Gdac1 Locus of Mice Deficient in Glutathione Peroxidase-1 and -2, Volume 7

By Bereswill, Stefan

Click here to view

Book Id: WPLBN0003933770
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos One : Analysis of Candidate Colitis Genes in the Gdac1 Locus of Mice Deficient in Glutathione Peroxidase-1 and -2, Volume 7  
Author: Bereswill, Stefan
Volume: Volume 7
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Bereswill, S. (n.d.). Plos One : Analysis of Candidate Colitis Genes in the Gdac1 Locus of Mice Deficient in Glutathione Peroxidase-1 and -2, Volume 7. Retrieved from http://ebooklibrary.org/


Description
Description : Among the remaining 10 genes, we identified Pla2g4f and Duox2 as the most likely colitis gene candidates, because GPX metabolizes PLA2G4F and DUOX2 products. Pla2g4f is a phospholipase A2 that has three potentially significant nsSNP variants and showed expression differences across mouse strains. PLA2G4F produces arachidonic acid, which is a substrate for lipoxygenases and, in turn, for GPXs. DUOX2 produces H2O2 and may control microbial populations. DUOX-1 and -2 control microbial populations in mammalian lung and in the gut of several insects and zebrafish. Dysbiosis is a phenotype that differentiates 129S1/SvImJ from C57BL/6J and may be due to strain differences in DUOX2 activity.

 

Click To View

Additional Books


  • Plos One : Methyl Fluoride Affects Metha... (by )
  • Plos One : Tannic Acid-dependent Modulat... (by )
  • Plos One : Ex-press Implantation Versus ... (by )
  • Plos One : Lentiviral Transduction of Cd... (by )
  • Plos One : Differential Expression of Cr... (by )
  • Plos One : Rhesus MacAque Theta Defensin... (by )
  • Plos One : Hprt-deficiency Dysregulates ... (by )
  • Plos One : Characterizing Venous Vascula... (by )
  • Plos One : the Protective Effects of the... (by )
  • Plos One : the Over-expression of an Ara... (by )
  • Plos One : Prenatal Exposure to Urban Ai... (by )
  • Plos One : Urban Tree Species Show the S... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.